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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIN1
All Species:
30.61
Human Site:
Y837
Identified Species:
61.21
UniProt:
Q05586
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05586
NP_000823.4
938
105373
Y837
L
I
F
I
E
I
A
Y
K
R
H
K
D
A
R
Chimpanzee
Pan troglodytes
XP_520645
886
94791
T799
P
C
W
T
K
P
R
T
G
L
P
G
G
P
R
Rhesus Macaque
Macaca mulatta
XP_001117773
867
97371
N785
Q
E
C
D
S
R
S
N
A
P
A
T
L
T
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P35438
938
105462
Y837
L
I
F
I
E
I
A
Y
K
R
H
K
D
A
R
Rat
Rattus norvegicus
P35439
938
105490
Y837
L
I
F
I
E
I
A
Y
K
R
H
K
D
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513355
491
55463
R409
S
V
D
I
Y
F
R
R
Q
V
E
L
S
T
M
Chicken
Gallus gallus
NP_996862
965
108202
Y835
L
I
F
I
E
I
A
Y
K
R
H
K
D
A
R
Frog
Xenopus laevis
NP_001081616
883
99412
S798
V
R
Y
Q
E
C
D
S
R
S
N
A
P
A
T
Zebra Danio
Brachydanio rerio
NP_001137603
937
105640
Y853
L
I
F
I
E
I
A
Y
K
R
H
K
D
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24418
997
112270
Y856
L
I
I
I
E
V
I
Y
K
K
H
Q
V
K
K
Honey Bee
Apis mellifera
NP_001011573
953
106251
Y847
L
I
I
I
E
V
A
Y
K
K
H
Q
I
R
K
Nematode Worm
Caenorhab. elegans
NP_495033
1025
115987
Y861
L
S
F
V
E
V
S
Y
G
R
R
L
A
D
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.9
80.3
N.A.
N.A.
99
99.2
N.A.
50.5
88.9
85.6
84.5
N.A.
44.5
47.8
32.2
N.A.
Protein Similarity:
100
40.5
82.3
N.A.
N.A.
99.6
99.6
N.A.
51.8
92.6
90.7
89.9
N.A.
64.2
67.4
51.2
N.A.
P-Site Identity:
100
6.6
0
N.A.
N.A.
100
100
N.A.
6.6
100
13.3
100
N.A.
46.6
53.3
33.3
N.A.
P-Site Similarity:
100
20
6.6
N.A.
N.A.
100
100
N.A.
20
100
40
100
N.A.
73.3
80
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
50
0
9
0
9
9
9
50
0
% A
% Cys:
0
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
9
0
0
0
0
0
42
9
0
% D
% Glu:
0
9
0
0
75
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
50
0
0
9
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
17
0
0
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% H
% Ile:
0
59
17
67
0
42
9
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
59
17
0
42
0
9
25
% K
% Leu:
67
0
0
0
0
0
0
0
0
9
0
17
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
9
0
0
0
0
9
0
0
0
9
9
0
9
9
0
% P
% Gln:
9
0
0
9
0
0
0
0
9
0
0
17
0
0
0
% Q
% Arg:
0
9
0
0
0
9
17
9
9
50
9
0
0
9
50
% R
% Ser:
9
9
0
0
9
0
17
9
0
9
0
0
9
0
0
% S
% Thr:
0
0
0
9
0
0
0
9
0
0
0
9
0
17
9
% T
% Val:
9
9
0
9
0
25
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _